【摘要】 目的:评价超脉冲CO₂点阵激光联合外用药膏治疗顽固性白癜风的临床疗效。方法:将56例顽固性白癜风患者随机分成治疗组29例（皮损52块）和对照组27例（皮损48块）,均外用丙酸氟替卡松乳膏及卡泊三醇每日1次,疗程12周。治疗组另给予CO₂点阵激光治疗,1次/3周,共4次。12周后评价疗效。结果:治疗组中有效皮损36块,有效率76.6%;对照组有效皮损18块,有效率42.9%,差异有显著性（P<0.01）。结论:点阵激光联合外用药物治疗白癜风比单用药物疗效明显。更多还原

【Abstract】 Objective: To assess the efficacy and safety of CO₂ fractional laser combined with topical hormone creams in the treatment of intractable vitiligo. Methods: Fifty six patients with intractable vitiligo were randomly divided into treatment group（ 29 patients with 47 lesions） and control group（ 27 patients with 42 lesions）. All the patients were treated with topical fluticasone propionate 0. 05% cream and calcipotriol ointment,once a day for 12 weeks and the patients in the treatment group were given additional CO₂ fractional laser,once three weeks for 4 times. The efficacy in the two groups was assessed. Results: Thirty-six lesions improved in the treatment group,giving an effective rate of 76.6% and 18 lesions improved in the control group,giving an effective rate of 42. 9%,with a significant difference between the two groups（ P < 0. 01）. Conclusion: CO₂ fractional laser combined with topical creams in treatment of intractable vitiligo is more effective than topical creams alone.更多还原