【摘要】 目的探讨幽门螺杆菌(Hp)感染与慢性荨麻疹(CU)之间的相关性。方法通过在万方数据库、中国期刊全文数据库(CNKI)、维普中文期刊数据库(VIP)以及Pubmed中检索相关文献,根据文献纳入排除标准,剔除和筛选所有文献后进行质量评价,运用Meta分析方法综合判断两者的相关性,运用Rev Man 5.2软件计算合并OR值和95%CI。结果入选的文献共有30篇,其中英文有7篇,中文有23篇,累计慢性荨麻疹病人3 401人,健康对照组4 214人。荨麻疹患者组中幽门螺杆菌感染的阳性率明显高于健康对照组,差异具有统计学意义(P<0.05)。结论幽门螺杆菌感染与慢性荨麻疹间存在相关性。更多还原

【Abstract】 Objective To investigate the association between Helicobacter pylori infection and chronic urticaria. Methods The literatures were searched in Wanfang,CNKI,CQVIP databanks and Pub Med.The quality of all the remaining literatures was evaluated according to the inclusion and exclusion criteria.Then,using Mate analysis method to determine the correlation between the Helicobacter pylori infection and Chronic urticaria. The OR value and 95% CI were calculated by using Rev Man 5. 2 software. Results 30 articles were selected,including 7 in English and 23 in Chinese. There were 3 401 patients with chronic urticaria and 4 214 healthy controls. The positive rate of Helicobacter pylori was higher in the Chronic Urticaria group than that in the healthy control group. The difference was statistically significant(P < 0. 05).Conclusion There was a certain correlation between Helicobacter pylori infection and Chronic Urticaria.更多还原