This paper measured the levels of end-users' acceptance and use of e-library service by employing multiple methods based on UTAUT model, and analyzed the factors influencing end-users' behavioral intentions and usage on accepting and using e-library service. The results showed 57 percent of variances existed in end-users' acceptance and use of e-library service in the universities of Inner Mongolia area, and social influence played a significant role in end-users' acceptance and use of e-library service.