【摘要】 目的观察不同剂量百草枯中毒(PQ)患者采用血液灌流(HP)治疗的疗效及对患者预后的影响。方法纳入2013年6月至2016年6月PQ中毒的38例患者,根据患者中毒剂量分为A组(<25ml)为10例,B组(25~40ml)为17例,C组(>40ml)为11例,比较三组患者经HP和常规治疗的疗效,并测定经HP治疗后的降钙素原(PCT)水平。结果 A组和C组经HP治疗与常规治疗(非HP治疗)预后对比无统计学意义(P>0.05),B组经HP治疗较非HP治疗死亡人数较少。经过HP治疗后,三组中C组PCT水平较其他两组低,对比具有统计学意义(P<0.05)。结论中毒剂量在25~40ml的患者经常规治疗后采用HP治疗可显著提高疗效并有效改善患者的预后,具有较高的临床应用价值。更多还原

【Abstract】 Objective To observe the efficacy of hemoperfusion in patients with paraquat poisoning and its influence on prognosis. Methods From June 2013 to June 2016,38 patients with PQ poisoning,according to the poisoning dose,10 patients were divided into group A( < 25ml),group B( 25 ~ 40ml) was 17 cases,group C( more than 40ml) was 11 cases.The efficacy of HP and conventional therapy was compared in three groups,and the levels of procalcitonin( PCT) after HP treatment were measured. Results There was no statistically significant difference in the prognosis between group A and group C( P > 0. 05). There were fewer deaths in group B compared with non-HP. The level of PCT in group B was lower than that in the other two groups after HP treatment( P < 0. 05). Conclusion The dose of 25 ~ 40 ml in patients after conventional treatment with HP treatment can significantly improve the efficacy and improve the prognosis of patients,with high clinical value.更多还原