【摘要】 目的回顾性分析2型糖尿病胰岛素抵抗与非酒精性脂肪肝的相关性。方法回顾性分析432名2型糖尿病患者的临床资料,其中2型糖尿病无非酒精性脂肪肝患者205例,2型糖尿病合并非酒精性脂肪肝患者227例,分别测定两组患者的空腹血糖、空腹胰岛素,计算反映胰岛素抵抗的胰岛素抵抗指数(HOMA-IR),比较各组不同指标的差异。结果 T2DM合并非酒精性脂肪肝病组的HOMA-IR高于T2DM无非酒精性脂肪肝病组(P<0.05)。logistic回归分析显示在校正了相关因素后,较高的Ln IR水平是发生NAFLD的独立危险因素。结论 2型糖尿病患者非酒精性脂肪肝病的发生与胰岛素抵抗密切相关。更多还原

【Abstract】 Objective To retrospective analysis the relationship between insulin resistance and nonalcoholic fatty liver disease in type 2 diabetes mellitus. Methods The clinical data of 432 patients with T2 DM were retrospectively analyzed.With no more than 205 patients with alcoholic fatty liver in type 2 diabetes,type 2 diabetes mellitus and 227 patients with nonalcoholic fatty liver disease,two groups of patients were separately measured fasting plasma glucose,fasting insulin,calculate reflect the insulin resistance index of insulin resistance( HOMA IR),comparing the difference between the groups of different indicators. Results HOMA- IR of T2 DM with nonalcoholic fatty liver disease group is higher than T2 DM without nonalcoholic fatty liver disease group( P < 0. 05). Logistic regression analysis revealed that after the correction of the related factors,a higher level of Ln IR are independent risk factors of NAFLD. Conclusion In patients with type 2 diabetes of nonalcoholic fatty liver disease is closely related to insulin resistance.更多还原