外周型单病灶肺结节临床资料与术后病理的多因素分析

【摘要】 目的 通过对术后病例资料的回顾性分析,研究外周型孤立性肺结节的临床资料与术后病理的关系。方法 收集术后病理诊断明确的病例资料,记录一般资料,同时对术前CT进行重新阅读,记录CT的各项特征。通过单因素方差分析和多因素cox回归分析,判断术前资料和CT的特征与术后病理结果 良恶性之间的关系。结果 外周型孤立性肺小结节是否恶性与结节的CT值、结节的大小、有无血管滋养、是否有毛刺以及实性成分占比有关,与患者年龄、性别、肿瘤位置、是否吸烟、结节边缘是否规则以及边界是否清晰无关。结论 外周型孤立性肺结节CT值越小,肿瘤直径越大,有血管滋齐,有毛刺,实性成分越少恶性风险越高。更多还原

【Abstract】 Objective To assess the relationship between the radiological characteristics and the pathological outcomes in peripheral pulmonary nodules.Methods A retrospective study was conducted on patients with resected lung nodules between Jan 2014 and Jan 2015.Clinical parameters and imaging features were analyzed using univariate and multivariate logistic regression analysis.Results Following multivariate analysis,except for sex,age,nodule location,the history of smoking,shape and the margin of the nodules,the CT attenuation,nodule size,signs of vascular convergence,spiculation and the solid proportion were found to be associated with malignant pathologic outcomes.Conclusions For peripheral isolated lung nodules,the larger in size,smaller in CT attenuation and the lower solid proportions,the more tendency they are of maligancy.The signs of vascular convergence and spiculation are also highly correlated with the malignancy.更多还原