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醒脑益智汤联合西药治疗血管性痴呆60例疗效观察

The Treatment of Vascular Dementia Combined Xing Nao-Yi Zhi Tang with Western Medicine—A Clinical Observation on 60 Patients

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【作者】 刘建华宏亚丽

【Author】 LIU Jian-hua;HONG Ya-li;College of Qibo Medical,Longdong University;

【机构】 陇东学院岐伯医学院

【摘要】 目的:观察醒脑益智汤联合西药治疗血管性痴呆的临床疗效。方法:将确诊的血管性痴呆患者120例,随机分为治疗组和对照组各60例,在常规对症治疗的基础上,对照组给予舒血宁、脑苷肌肽、阿司匹林、多奈哌齐治疗;治疗组在对照组的基础上,加服醒脑益智汤治疗。2组疗程均为1年,观察2组患者治疗前后简易精神状态检查量表(MMSE)评分、日常生活能力量表(ADL)评分,评价临床疗效。结果:治疗组总有效率93.3%,对照组总有效率81.7%,2组疗效比较差异有显著性意义(P<0.01)。治疗组治疗后MMSE、ADL评分与治疗前比较差异均有显著性意义(P<0.01);与对照组治疗后比较差异均有显著性意义(P<0.05)。结论:醒脑益智汤联合西药治疗血管性痴呆的临床疗效优于单纯西药治疗,且副作用相对较少。

【Abstract】 Objective:to observe the effect of Xing Nao-Yi Zhi Tang combined with western medicine on treating vascular dementia.Methods:120 patients with vascular dementia were randomly divided into two groups--treatment group and control group,each group had 60 cases.The control group was given Shu Xuening Tablet,cerebroside-kinin,aspirin and donepezil while the treatment group was treated by Xing Nao-Yi Zhi Tang with Shu Xuening Tablet,cerebroside-kinin,aspirin and donepezil.A treatment course lasts 2 years for each group.We observed the changes of MMSE and ADL to evaluate clinical curative effect.Results:total efficiency of the treatment group was 93.3% while the total efficiency of control group was 81.7%.There were significant difference between the two groups(p < 0.01); It had significant difference in the scores of MMSE and ADL before and after for treatment group(p < 0.01);compared with the scores for the control group after treating,there was also significant difference.Conclusions:the clinical effect of Xing Nao-Yi Zhi Tang with western medicine was superior to western medicine treatment alone and had fewer side effects.

  • 【文献出处】 陇东学院学报 ,Journal of Longdong University , 编辑部邮箱 ,2017年01期
  • 【分类号】R749.13
  • 【被引频次】6
  • 【下载频次】82
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