Summary Immune thrombocytopenic purpura(ITP)is an acquired disease with detectable autoantibodies against antigens on platelets'surface,which accelerate platelets'destruction and inhibit their production.In most cases,ITP are considered be idiopathic;whereas others are secondary to some well-defined causes including autoimmune disease,immunodeficiency and drug.Recent studies suggest that the proclivity to develop platelet-reactive antibodies in secondary ITP is resulted from diverse mechanisms.ITP secondary...
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