【摘要】 目的 探讨无抽搐电休克治疗撤药反应的疗效及安全性。方法 采用掷硬币法,将83例撤药反应患者分为研究组和对照组,分别采用无抽搐电休克治疗及对症抗精神类药物治疗,在治疗前及治疗第11 d采用谵安严重程度量表评分比较疗效。结果 治疗第11 d,研究组和对照组的量表分较治疗前均差异有统计学意义(P<0.01);与对照组相比,研究组量表分差异有统计学意义(P<0.01)。结论无抽搐电休克治疗氯氮平撤药后谵妄快速、有效,值得临床试用。更多还原

【Abstract】 Objective To explore the efficacy and safety of modified electric convulsive therapy（MECT）for withdrawal reactions.Methods According to coin-throwing 83 patients with withdrawal reactions were divided into research and control group treated with MECT and symptomatic antipsychotic respectively,efficacies were compared according to Delirium Severity Scale（DSS） score before treatment and on the 11 th day of treatment.Results On the 11^th day of treatment the DSS scores of both groups had statistical differences from those before treatment（P<0.05）,intergroup difference of DSS scores had significant significance（P<0.05）.Conclusion MECT is quick and effective in the treatment of clozapine withdrawal resulting in delirium and deserves clinical trial.更多还原