【摘要】 目的 探讨重复经颅磁刺激对于精神分裂症患者认知功能的影响,并且以P300评定重复经颅磁刺激治疗后的认知障碍疗效,同时威斯康星卡片测评进行对照研究。方法 将60例精神分裂症患者随机分为实验组与对照组,实验组运用重复经颅磁刺激治疗,对照组未进行干预。治疗后两组行认知功能测评,比较神经心理学量表威斯康星量表分值及P300波幅、潜伏期。结果精神分裂症患者在重复经颅磁刺激治疗后的神经心理学的测验成绩提高,P300的潜伏期缩短,波幅提高,实验组与对照组存有显著性差异(P<0.05或0.01)。结论 本研究提示重复经颅磁刺激治疗对于慢性精神分裂症患者的精神病性症状及认知功能有改善作用。更多还原

【Abstract】 Objective To explore the influence of repetitive transcranial magnetic stimulation(rTMS) on the cognitive functions of schizophrenia patients,to assess the efficacy of post-rTMS cognitive disorders using P300,and to assess with the Wisconsin Card Sorting Test(WCST).Methods Sixty schizophrenics were randomly assigned to experimental and control group,experimental group was treated with the rTMS,and the control wasn’t.After rTMS cognitive functions of both groups were assessed and the WCST scores and P300 amplitudes and latencies compared between the 2 groups.Results After rTMS the WCST scores heightened,P300 latencies shortened,and amplitudes heightened,there were significant group differences(P<0.05 or 0.01).Conclusion The rTMS could improve the psychotic symptoms and cognitive function of patients with chronic schizophrenia.更多还原