Objective To understand TB drug resistance in initial-treated positive pulmonary tuberculous patients during different periods,in order to provide basis of the establishment and improvement of TB control. Methods Through collecting the patients` sputum cultures of 1993. 1-1995. 12( the period A) and 2013. 1-2015. 12( the period B),the drug sensitivity test results of 501 initial-treated patients( 90 in period A and 411 in period B)were analyzed. Results The TB total resistant rate of the two periods were 62...