【摘要】 目的探讨短暂性脑缺血发作进展为脑梗死的相关因素。方法对2012年1月—2017年4月我院短暂性脑缺血发作患者132例进行随访观察,将进展为脑梗死的患者作为观察组,未进展为脑梗死患者作为对照组,比较两组患者年龄、性别、首次发作就诊时间、发作次数、持续时间、基础疾病、吸烟史、二级预防依从性的差异。结果进展为脑梗死40例(30.30%)。观察组男性比例(70.00%)、首次发作就诊时间(26.78±5.08)h、持续时间(30.16±6.38)min、发作次数(3.53±0.87)次、基础疾病(95.00%)、吸烟史(55.00%)、二级预防依从性差(42.50%)高于对照组的45.65%、(11.39±3.48)h、(14.30±4.28)min、(1.86±0.72)次、65.22%、26.09%、21.74%(t/χ2=7.43、8.28、5.70、8.33、9.76、9.53、5.87,P<0.05),两组年龄[(67.87±6.87)岁vs.(66.00±6.59)岁]差异无统计学意义(t=0.28,P>0.05)。结论短暂性脑缺血发作进展为脑梗死是多种因素共同作用形成的结果,应制定合理、有效预防措施,以降低脑梗死的发生率。更多还原

【Abstract】 Objective To explore the related factors that lead to the progression of transient ischemic attack to cerebral infarction. Methods Transient ischemic attack patients 132 cases in our hospital from January 2012 to April 2017 were followed up. The patients who have progressed to cerebral infarction as the observation group, no progress was made in patients with cerebral infarction as a control group.The differences betweentwo groups in age, gender, time of first visit, frequency of attack, duration, underlying disease, smoking history and compliance were compared. Results The progress was 40 cases of cerebral infarction(30.30%). In observation group, the proportion of male(70.00)%, first attack time(26.78 ± 5.08) h, duration(30.16 ± 6.38) min, attack times(3.53 ± 0.87) times, basic disease(95.00%), smoking history(55.00%), two grade prevention compliance(42.50%), were higher than those in the control group of 45.65%,(11.39 ± 3.48) h,(14.30 ± 4.28) min,(1.86 ± 0.72) times, 65.22%, 26.09%, 21.74%(t/χ~2=7.43, 8.28, 5.70, 8.33, 9.76, 9.53, 5.87, P < 0.05). There was no significant difference between the two groups of age [(67.87 ± 6.87) years vs.(66.00 ± 6.59) years](t=0.28, P > 0.05). Conclusion Transient ischemic attack progresses to cerebral infarction is the result of combination multiple factors, should formulate reasonable and effective preventive measures to reduce the incidence of cerebral infarction.更多还原