【摘要】 目的:低钠血症对慢性心力衰竭(CHF)患者的影响。方法:将113例门诊复诊CHF患者按照入院时血钠水平分为常血钠组28例、低钠血症组85例;将低钠血症组根据血钠浓度的高低分为三组,轻度低钠血症组(血钠浓度130~134 mmol/L)41例、中度低钠血症34例(血钠125~129 mmol/L)、重度低钠血症(血钠<125 mmol/L)10例。测入院时患者血清中脑钠肽(BNP)水平,并对各组进行比较。结果:正常血钠组患者BNP值与低钠血症组比较,差异有统计学意义(P<0.05);轻度低钠血症组患者BNP值与中度低钠血症组比较,差异无统计学意义(P>0.05);轻度及中度低钠血症组患者BNP值与重度低钠血症组比较,差异有统计学意义(P<0.05)。结论:心力衰竭患者心脏功能的恶化与低钠血症相关,并与低钠血症的严重程度呈正相关。更多还原

【Abstract】 Objective To study that correction of hyponatremia and chronic heart failure( CHF).Method 113 CHF who administered diuretic medication were divided into 4 groups,including that normal group 28 cases,mild hyponatremia group(130 ~134 mmol/L) 41 cases,moderate hyponatremia group(125 ~ 129 mmol/L) 34 cases,severe hyponatremia group( < 125 mmol/L) 10 cases.Difference of brain natriuretic peptide( BNP) in various groups were compared.Results Normal serum sodium group value of BNP and hyponatremia patients had statistically significant difference( P < 0.05);there was no significant difference between mild and moderate hyponatremia value of BNP( P > 0.05);in the mild and moderate hyponatremia group,the value of BNP in patients with severe hyponatremia had statistical difference( P < 0.05).Conclusion The deterioration of cardiac function in patients with CHF is related to hyponatremia,and is positively correlated with the severity of hyponatremia.更多还原