【摘要】 皮肤间充质干细胞是一种在皮肤中分离到的间充质干细胞,它具有强大的分化潜能,并且能长期保持多能性.本文介绍了皮肤间充质干细胞的发现及其特性,探讨了皮肤间充质干细胞的来源问题,并回顾了皮肤间充质干细胞作为一种潜在的细胞疗法在中枢/外周神经损伤、骨损伤和皮肤创伤中的研究,介绍了皮肤间充质干细胞大规模生产的一些尝试,并提出了未来需要解决的关键性问题.更多还原

【Abstract】 Mesenchymal stem cells derived from skin have the capability of self-renewal and multipotent differentiation. They can maintain their multipotency even after passaging for extended periods of time. Here, we discuss how skin mesenchymal stem cells were discovered. We describe the properties of skin mesenchymal stem cells and discuss their origin.Furthermore, we review the application of skin mesenchymal stem cells as a potential cell-based therapy for the treatment of central/peripheral nerve injury, bone injury, and skin trauma. Studies on expanding the applications of skin mesenchymal stem cells are also reported here. Finally, we list several important scientific questions, associated with the use of skin mesenchymal stem cells, to be addressed in the future.更多还原