【摘要】 目的探究地屈孕酮及黄体酮治疗先兆性流产的临床效果。方法方便选取济南市第二人民医院妇产科2016年3月—2017年3月收治的98例先兆性流产患者临床资料进行分析,将行黄体酮治疗者作为对照组(49例),行地屈孕酮治疗者作为研究组(49例),比较两组保胎成功率、血清人绒毛膜促性腺激素(HCG)与孕酮(P)水平、不良反应发生率。结果研究组保胎成功率93.87%显著高于对照组(P<0.05);研究组与对照组治疗后HCG、P水平分别为(8 556.04±1 966.96)U/m L、(30.08±3.12)nmol/L以及(6 305.08±2 105.92)U/m L、(26.31±4.26)nmol/L,均较治疗前提升(P<0.05),研究组治疗后提升幅度大于对照组(P<0.05);研究组总不良反应率4.08%与对照组相比显著低(P<0.05)。结论先兆性流产采取地屈孕酮可有效提升疗效,且不良反应少,可推广。更多还原

【Abstract】 Objective To study the clinical effect of dydrogesterone and progesterone in treatment of threatened abortion.Methods 98 cases of patients with threatened abortion admitted and treated in our hospital from March 2016 to March 2017 were convenient selected and divided into two groups with 49 cases in each, and the success rate of preventing miscarriages and levels of HCG and P and incidence rate of adverse reactions were compared between the two groups. Results The success rate of preventing miscarriages in the research group was 93.87%, which was obviously higher than that in the control group(P<0.05), after treatment, the HCG and P levels in the research group and the control group were respectively(8 556.04±1 966.96)U/m L,(30.08±3.12)nmol/L and(6 305.08±2 105.92)U/m L,(26.31±4.26)nmol/L, which were obviously improved compared with those before treatment(P<0.05), and the improvement range after treatment in the research group was higher than that in the control group(P<0.05), and the total incidence rate of adverse reactions in the research group obviously decreased compared with that in the control group, which was 4.08% in the research group(P<0.05). Conclusion The dydrogesterone in treatment of threatened abortion can effectively improve the curative effect with adverse reactions, which can be promoted.更多还原