【摘要】 目的了解郑州地区妊娠期妇女TORCH感染情况及其流行特点,为本地区妊娠期妇女围产期保健提供参考。方法采用化学发光免疫方法对2013年1月至2016年12月收集的妊娠期妇女血清标本进行弓形虫(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)以及人疱疹病毒(HSV)的Ig M和Ig G抗体的检测。结果 24 510例妊娠期妇女血清中TOX-IgM、RV-IgM、CMV-IgM、HSV-IgM的阳性率分别为0.47%、0.85%、0.35%和1.31%,其中HSV-Ig M的阳性率最高;TOX-IgG、RV-IgG、CMV-IgG、HSV-IgG的阳性率分别为0.82%、46.27%、94.56%和91.08%。结论郑州地区TORCH的感染阳性率较高,应该提高对TORCH感染的重视,加强对孕妇TORCH IgG和IgM抗体筛查,早诊断、早干预,积极预防,这对人类的优生优育具有重要意义。更多还原

【Abstract】 Objective To investigate the prevalence and epidemic characteristics of TORCH infection in pregnant women in Zhengzhou area and provide reference for perinatal health care of pregnant women. Methods The serum of pregnant women were collected from January 2013 to December 2016,the IgM and IgG antibody of Toxoplasma gondii( TOX),rubella virus( RV),cytomegalovirus( CMV) and human herpes virus( HSV) were detected by chemiluminescence immunoassay method. Results The positive rates of TOX-IgM,RV-IgM,CMV-IgM and HSV-IgM in 24510 serum samples of pregnant women were 0. 47%,0. 85%,0. 35% and 1. 31%,respectively,the positive rate of HSV-IgM were the highest; The positive rates of TOX-IgG,RV-IgG,CMV-IgG and HSV-IgG were 0. 82%,46. 27%,94. 56% and 91. 08%,respectively. Conclusion The positive rates of TORCH infection were high in Zhengzhou area,thus the awareness of TORCH infection should be raised,the screening of TORCH IgG and IgM antibody should be strengthened in order to provide early diagnosis and intervention,also active prevention. It is of great significance to human eugenics.更多还原