【摘要】 目的探讨分析影响早期子宫颈癌患者手术治疗效果的高危风险因素,并观察上述因素对患者生存结局的影响。方法采用回顾性分析方法,选取早期(ⅠB~ⅡB期)宫颈癌患者98例,均经病理学证实且接受手术治疗。通过检测手术病理学风险因素,依据存在的风险因素数目将患者分组,组间比较手术疗效。结果存在1项风险因素者(单项组)33例(33.7%),存在多项(≥2项)者(多项组)23例(23.5%)。随访显示,多项组局部复发率和远处转移率高于单项组(P<0.05),而总生存期(OS)及无瘤生存期(DFS)低于单项组(P<0.05)。多项组中,接受同步放化疗者生存期均优于单纯放疗者(P<0.05)。结论在接受手术治疗的早期宫颈癌患者中,多项风险因素可降低手术效果和生存结局。同步放化疗有助于提高治疗效果。更多还原

【Abstract】 Objective To investigate the effects of high-risk factors on clinical outcomes of early-stage cervical cancer patients after surgical. Methods Totally 98 cases of pathologically confirmed early-stage cervical cancer patients were selected,and all received surgical treatment. Thesurgical-pathological risk factors of patients were analyzed and grouping according to the number of high-risk factors. The surgical results of groups were compared. Results There were 1 risk factors(single group) in 33 cases(33. 7%),multiple high-risk factors(≥2)(multiple group) in23 cases(23. 5%).The local recurrence rate and distant metastasis rate of multiple group were higher than that of single group(P < 0. 05),but the overall survival(OS) and disease-free survival(DFS) were lower than those the single group(P < 0. 05). The survival time in patients treated with synchronism chemoradiation were better than those with radiotherapy alone in multiple group(P < 0. 05). Conclusion Multiple risk factors can reduce surgical outcomes and survival outcomes of early-stage cervical cancer patients after surgical,and synchronism chemoradiation is helpful to improve clinical outcomes.更多还原