The effect of continuous phenylephrine infusion and single-dose phenylephrine injection on puerpera undergoing spinal and epidural combined anesthesia and the infant outcomes
目的探讨持续去氧肾上腺素静脉泵注与单次给药对腰硬联合麻醉下剖宫产产妇及新生儿的影响。方法 2015年7月—2016年6月选取50例腰硬联合麻醉下行剖宫产产妇为研究对象,随机分为去氧肾上腺素持续输注组(持续输注组,n=25),于麻醉后即刻予以0.5μg/(kg·min)去氧肾上腺素持续泵注调整血压;去氧肾上腺素单次给药组(单次给药组,n=25),于麻醉后收缩压<90 mm Hg(1 mm Hg=0.133 k Pa)或平均动脉压下降>基础值的20%时给予去氧肾上腺素50μg/次。取出胎儿后停止输注去氧肾上腺素。记录产妇入室(T_1)、麻醉前(T_2)、麻醉后1 min(T3)、麻醉后3 min(T_4)、麻醉后10 min(T_5)、取出胎儿时(T_6)的平均动脉压、心输出量、心指数,并抽新生儿脐动脉血进行血气分析并记录pH值、氧分压、二氧化碳分压、实际碳酸氢盐(HCO_3~–)、碱剩余,并对新生儿进行Apgar评分。结果持续输注组较单次给药组血流动力学更稳定,单次给药组在T_4、T_5时心率和在T_5、T_6时心输出量较持续输注组低(P<0.05);单次给药组新生儿脐动脉血的pH值、HCO_3~–、碱剩余均低...
【英文摘要】
Objective To discuss the effect of continuous phenylephrine infusion and single-dose phenylephrine injection on puerpera undergoing spinal and epidural combined anesthesia and the infant outcomes. Methods A total of50 patients scheduled for selective cesarean section under combined spinal and epidural anesthesia were selected as the study subjects between July 2015 and June 2016. They were randomly allocated into two groups with 25 in each. Group CII underwent continuous phenylephrine infusion [0.5 μg/(kg·m...
| 
推荐 
点击下列相关研究机构和相关文献作者，可以直接查到这些机构和作者被《中国知识资源总库》收录的其它文献，使您全面了解该机构和该作者的研究动态和历史。
