【摘要】 采用质谱(MS)和核磁共振谱(NMR)对原料苯氧乙醇进行定性分析,优化并建立了液相色谱法及气相色谱法测定苯氧乙醇,纯度为99.3%。以甲醇为基体溶液,采用重量-容量法制备苯氧乙醇标准物质。以液相色谱(紫外法、示差法)两种方法进行定值,并做了均匀性检验和稳定性跟踪。建立不确定度评定方法,标准物质特性值为99.3(±1.1)μg/mL(k=2)。苯氧乙醇标准物质具有溯源性和准确性,对于化妆品中防腐剂苯氧乙醇含量的准确测定及监控具有重要意义。更多还原

【Abstract】 GC-MS and NMR were used to confirm the structure of phenoxyethanol.HPLC and GC were used to determine the purity of phenoxyethanol,and the purity was revealed to be 99.3%.Phenoxyethanol reference was prepared in methanol according to weight-capacity method.Ultraviolet and differential spectrophotometry were used for certificating the value,the homogeneity and stability.The uncertainty of this evaluation method was established.The property value of phenoxyethanol was 99.3(± 1.1)μg/mL(k=2).The standard phenoxyethanol reference prepared in this study was traceable and accurate,and it can be used as a standard reference for preservative analysis of cosmetics.更多还原