Objective To explore the association of the single nucleotide polymorphism(SNP)of rs11970286 with QT interval and ventricular tachycardia(VT)in Chinese Han population.Methods A total of 242 patients with VT(VT group)and 1 002 healthy subjects(control group)underwent electrocardiography to measure heart rate,PR interval,QRS duration,QT interval and QTc interval.Both two groups were genotyped for rs11970286 using a Rotor-Gene TM 6000 High Resolution Melt system after extraction of peripheral blood DNA.The cor...
【基金】
河南省科技攻关项目(201602214)
【更新日期】
2017-11-03
【分类号】
R541.71
【正文快照】
室性心动过速(室速)是一种严重快速心律失常,周血置于EDTA抗凝管,应用Promega公司Wizard?其中不伴有器质性疾病、代谢及电解质异常、长QT间Genomic DNA Purification Kit提取基因组DNA。基期综合征的室速称为特发性室速[1-2]。QT间期代表因分型采用高分辨熔解曲线分析(high?