Objective To explore the value of virtual touch tissue imaging quantification(VTIQ)to the diagnosis of median nerve stiffness of carpal tunnel syndrome(CTS).Methods Forty-nine patients(72 wrists)with CTS(CTS group)and 23 healthy volunteers(46 wrists)(control group)received two-dimensional ultrasound to measure the cross-sectional area(CSA),and VTIQ was adopted to measure the shear wave velocity(SWV)of the median nerve at the entrance of the carpal tunnel.ROC was drawn to calculate the efficiency of median n...