【摘要】 环氧化物水解酶可高效率、高选择性地水解环氧化物生成手性邻二醇,对光学活性的邻二醇的合成和光学活性的环氧化物的制备具有重要意义.文章阐述了环氧化物水解酶的作用、来源、结构及其催化机制,进一步综述了环氧化物水解酶催化环氧化物水解、环氧化物水解酶的克隆表达等研究进展.更多还原

【Abstract】 Epoxide hydrolases can highly and selectively catalyze epoxides to chiral diols,which is an effective way to synthesize chiral diols. This article introduces the structure,functions,sources and mechanism of catalysis of this enzyme. The research on the hydrolyzation of epoxides by epoxide hydrolases,the enzyme cloning and expression in other bacteria are summarized.更多还原