【摘要】 目的探讨经皮肾镜碎石术(PCNL)后感染性休克的早期预警指标及其对血清细胞因子的影响。方法选取2015-01—2015-12间贵港市人民医院收治的PCNL术后感染性休克患者32例为研究组,选取同期术后未感染患者32例为对照组,对比两组患者早期预警指标以及血清细胞因子水平。结果两组患者的血生化指标对比方面,研究组患者的DD(D二聚体)以及TNT(肌钙蛋白)水平显著高于对照组,CHE(胆碱酯酶)以及ALB(白蛋白)水平明显低于对照组,差异有统计学意义(P<0.05);两组患者的血清细胞因子对比方面,研究组血清当中的IL-6(白介素-6)、IL-10(白介素-10)、CRP以及TNF-α水平均显著高于对照组,差异有统计学意义(P<0.05)。结论 PCNL患者血清炎性细胞因子水平显著上升,是感染性休克的重要预警指标,需要做好相应的干预措施。更多还原

【Abstract】 Objective To investigate the early warning index of septic shock after percutaneous nephrolithotomy(PCNL) and its effect on serum cytokines.Methods 32 patients with PCNL postoperative septic shock enrolled in the hospital from January to December,2015 were regarded as the study group.32 uninfected patients were selected as the control group.The early warning indexes and serum cytokine levels of the two groups were compared.Results The levels of DD(D-dimer) and TNT(troponin) in the study group were significantly higher than those in the control group,CHE(cholinesterase) and ALB(albumin) were significantly lower than those in the control group.There was statistical significant difference(P < 0.05).In the serum cytokines,(IL-6) and IL-10(interleukin-10) of the study group were significantly lower than those in the control group.There was statistical significant difference(P < 0.05).Conclusion The level of serum inflammatory cytokines in PCNL patients increases significantly,which is an important early warning index of septic shock,so the corresponding intervention measures need to be done.更多还原