The aim of the present studywas to identify the effect of induced pluripotent stem cell-conditioned medium(iPSC-CM) on the proliferation and oxidative stress of myoblasts. The C2C12 myoblasts were divided into six groups: C2C12 myoblasts in group A were cultured normally; part of original medium for C2C12 myoblasts in group B and C were replaced by 25% and 50% iPSC-CM,respectively. In group A',B' and C',the C2C12 myoblasts were treated by 100 μmol/L H_2O_2 respectively based on the same culture medium as th...