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维持性透析患者继发性甲状旁腺功能亢进的危险因素研究

Research of Risk Factors for Secondary Hyperparathyroidism in Patients Undergoing Maintenance Dialysis

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【作者】 梁伟姜蕾陈丽

【Author】 Liang Wei;Jiang Lei;Chen Li;Department of Nephrology,the Shenzhen Hospital of Peking University;

【机构】 北京大学深圳医院肾内科

【摘要】 目的探讨分析维持性透析(Maintenance dialysis,MD)患者继发性甲状旁腺功能亢进(Secondary hyperparathyroidism,SHPT)的危险因素。方法选取我院2015年1月至9月间长期透析治疗的472例患者作为研究对象,分析所选患者临床资料,使用单因素、多因素分析MD患者继发性甲状旁腺功能亢进的危险因素。结果经单因素分析显示,透析年龄、年龄、血磷、钙、钙磷乘积均和MD患者SHPT存在关系,具有统计学意义(P<0.05)。而女性MD患者出现SHPT症状的可能性更大。维持性透析患者出现SHPT的独立性危险因素为年龄,年龄降低1岁,出现SHPT的风险性则增加21%左右。透析年龄增高1年,出现SHPT的风险性则增加54%左右。结论透析龄和年龄可能是导致MD患者出现SHPT的危险性因素。

【Abstract】 Objective To probe into and analyze the risk factors for secondary hyperparathyroidism in patients undergoing maintenance dialysis.Methods 472 patients with MD and who accepted treatments in our hospital from January to September,2015 were taken as the research objects,and the clinical data of selected patients were retrospectively analyzed.Then,the risk factors of MD patients with excited parathyroid function were analyzed by the multiple factors,single factor.Results After single factor analysis,it was found that dialysis age,age,blood phosphorus,calcium,calcium and phosphorus products were related to SHPT patients with MD,and there was a certain difference in the data,with statistical significance(P<0.05).And female MD patients with SHPT symptoms were more likely.In addition,MD patients with SHPT independent risk factors for age,age decreased one year old,the risk of SHPT appears to be increased by about 21% or so.Dialysis age increased one year,the risk of SHPT increased by about 54%.Conclusion The dialysis age and age were both risk factor for MD in patients with SHPT.

  • 【文献出处】 哈尔滨医药 ,Harbin Medical Journal , 编辑部邮箱 ,2017年03期
  • 【分类号】R582.1;R692.5
  • 【下载频次】43
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