【摘要】 目的对雷公藤根的化学成分进行研究。方法综合运用硅胶柱色谱、凝胶色谱和半制备型高效液相等色谱方法进行系统分离,根据化合物的理化性质及其波谱数据确定化合物的结构。结果雷公藤根中分离出6个化合物,分别鉴定为:3,3-二甲基鞣花酸(3,3,di-O-methyellagic acid)(1)、1,2-没食子酰丙三醇(1,2-O-di-galloylglycerol)(2)、14β-hydroperoxy-eburnamine(3),(-)-syringaresino(4),(-)-melilotocarpan A(5)、(9R,10E,12E)-9-methoxyoctadecadienoic acid(6)。结论化合物2~6首次从雷公藤属植物中分离得到。更多还原

【Abstract】 OBJECTIVE To study the chemical constituents from roots of Tripterygium wilfordii. METHODS The fraction was sequentially subjected to silica gel,Sephadex LH-20 and semi-preparative HPLC. RESULTS 6 compounds were isolated from Tripterygium wilfordii,and identified as 3,3,di-O-methyellagic acid(1),1,2-O-di-galloylglycerol(2),14β-hydroperoxy-eburnamine(3),(-)-syringaresino(4),(-)-melilotocarpan A(5),(9 R,10 E,12 E)-9-methoxyoctadecadienoic acid(6). CONCLUSION Compounds 2-6 were isolated from the genus Tripterygium for the first time.更多还原