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BNP或NT-proBNP对冠心病的临床意义

Clinical significance of BNP or NT-pro BNP in coronary heart disease

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【作者】 李立健饶绍奇田镭钢梁岩

【Author】 LI Li-jian;RAO Shao-qi;TIAN Lei-gang;LIANG Yan;Graduate School,Guangdong Medical University;Institute of Systems Biomedicine and School of Public Health,Guangdong Medical University;Department of Cardiology,Maoming People’s Hospital;

【机构】 广东医科大学研究生院广东医科大学医学系统生物学研究所与公共卫生学院茂名市人民医院心内科

【摘要】 冠心病是最常见的心血管疾病,其发病率、死亡率一直居高不下,甚至有人预测到2020年冠心病将成为全球人口最主要的死亡病因。因此早期识别、诊断冠心病,并及时干预、治疗以阻止冠心病进一步发展显得尤为重要。关于BNP或NT-proBNP与冠心病(CHD)的关系,不少人进行了研究,表明BNP或NT-proBNP能反映冠心病的危重程度,并有助于冠心病的诊断及预后判断。

【Abstract】 Coronary heart disease, the most common cardiovascular disease, has always been characterized with high morbidity and mortality. It is predicted that coronary heart disease would become the main cause of death in the world by 2020. Therefore, early recognition and diagnose of coronary heart disease, and timely intervention and treatment to prevent further development of the disease have become very important. Many experts have studied the relationship between brain natriuretic peptide(BNP) or N-terminal pro-brain natriuretic peptide(NT-pro BNP) and coronary heart disease(CHD), which shows that BNP or NT-pro BNP could reflect the severity of coronary heart disease and provide useful information about diagnose and prognosis of coronary heart disease.

【关键词】 BNPNT-proBNP冠心病临床意义
【Key words】 BNPNT-proBNPCoronary heart diseaseClinical significance
【基金】 国家自然科学基金(编号:31071166、81373085);广东省科技计划攻关项目(编号:2009A030301004);广东省东莞市科技重点项目(编号:201108101015);广东医学院基金(编号:XG1001、JB1214、XZ1105、STIF201122)
  • 【文献出处】 海南医学 ,Hainan Medical Journal , 编辑部邮箱 ,2017年05期
  • 【分类号】R541.4
  • 【被引频次】26
  • 【下载频次】376
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