【摘要】 目的分析慢性阻塞性肺疾病(AECOPD)患者的血清降钙素原(PCT)水平与APACHE Ⅱ评分的临床关系。方法任选90例急性加重期的慢性阻塞性肺疾病患者开展研究,根据我院对90例患者进行APACHE Ⅱ评分的结果,按照分数高低方式分为低危组(30例)、中危组(30例)和高危组(30例),此外,根据血清降素原检查的结果,将病患分为非细菌感染组(20例)和细菌感染组(70例),分析低、中、高危三组患者PCT水平的高低差异性,分析三组患者PCT水平与APACHE Ⅱ评分高低的关系,并分析PCT水平对评价病患是否为细菌感染病患的指导作用。结果低、中、高危三组病患PCT水平呈现递增关系[(0.2±0.1)ng/mL<(0.4±0.2)ng/mL<(0.6±0.3)ng/mL],AECOPD病患PCT水平与APACHE Ⅱ评分具有正相关关系;PCT水平对鉴定细菌感染病患和非细菌感染病患具有指导作用,可以为临床使用抗生素提供参考。结论 AECOPD患者PCT水平与APACHE Ⅱ评分在临床上具有正相关关系,可以将PCT水平和APACHE Ⅱ评分作为评价AECOPD病患病情严重程度的标准。更多还原

【Abstract】 Objective To analyze the clinical relationship of PCT levels and APACHE Ⅱ score about acute exacerbation of chronic obstructive pulmonary disease(AECOPD) patients. Methods 90 patients of AECOPD were selected to conduct a research. According to the results of APACHE Ⅱ score and the score high and low, they were divided into low risk groups(30 cases), middle risk groups(30 cases) and high-risk groups(30 cases). In addition, according to the results of PCT test, the patients were divided into non-bacterial infection groups(20 cases) and bacterial infections(70 cases). The PCT level height-low difference of three groups were analyzed. Then the relationship of PCT levels and APACHE II score about three groups were analyzed. The PCT level to evaluate whether patients for bacterial infection patients was analyzed. Results The PCT level of the three groups of patients with low, middle and high risk was increased[(0.2±0.1)ng/mL <(0.4±0.2)ng/mL <(0.6±0.3)ng/mL], and the PCT level of patients with AECOPD was positively correlated with the APACHE II score. PCT level provided guidance for identifying patients with bacterial infections and non-bacterial infections, and it could provide a reference for clinical use of antibiotics. Conclusion The PCT level of the AECOPD patients and the APACHE Ⅱ score are clinically positive, the PCT level and the APACHE Ⅱ score can be used to evaluate the severity of the disease in AECOPD.更多还原