【摘要】 目的探讨阿奇霉素给药途径对小儿肺炎患儿用药依从性及效果的影响。方法 2014年2月~2016年2月我院接收的小儿肺炎患儿84例,根据阿奇霉素用药途径随机分为口服组、静脉组,各42例,对比两组患儿疗效、症状改善时间、治疗依从性及不良用药反应。结果两组患儿临床疗效、症状消失时间及住院时间差异无统计学意义(P>0.05);口服组治疗依从性为85.71%显著高于静脉组59.52%,不良用药反应为7.14%显著低于静脉组23.81%,差异有统计学意义(P<0.05)。结论口服阿奇霉素疗效与静脉给药大致相同,但与后者相比,前者具有不良反应少、用药便利的优势,能提高患儿治疗依从性。更多还原

【Abstract】 Objective To explore the effect of administration route of azithromycin on medication compliance and curative effect in children with pneumonia. Methods 84 children with pneumonia who were admitted to the hospital from February 2014 to February 2016 were included in the study.According to the administration routes of azithromycin,they were divided into the oral group and the intravenous group,with 42 in each.Curative effects,time for symptoms improvement,treatment compliance and adverse drug reactions between the two groups were compared. Results Clinical curative effect,disappearing time for symptoms and hospitalization stay between 2 groups has no difference(P > 0.05).Treatment compliance of the oral group was 85.71%,significantly higher than that of intravenous group 59.52%.While the rate of adverse drug reaction of the oral group was 7.14%,significantly lower than that of intravenous group 23.81%(P < 0.05). Conclusion The curative effects of oral azithromycin and intravenous administration are similar.But compared with the latter,the former has fewer adverse reactions and convenient medication,which can improve treatment compliance of children.更多还原