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新疆阿魏化学成分及药理活性研究进展
Chemical constituents and pharmacological activities of Ferula sinkiangensis K.M.Shen:research advances
【摘要】 新疆阿魏(Ferula sinkiangensis K.M.Shen)是分布在新疆北部的濒危民族植物药,主要含有倍半萜香豆素、含硫化合物、多糖和芳香族类等多种有效化学成分。目前多采用色谱技术建立指纹图谱实现质量控制。原植物药和特征化合物都具有抑菌、杀虫、抗过敏、抗肿瘤等广泛药理作用。本文主要从资源现状、化学成分、指纹图谱和药理活性等方面对国内外新疆阿魏的研究状况进行综述,为其系统化研究、有效质量控制和高效开发利用提供参考。
【Abstract】 Ferula sinkiangensis K.M. Shen is a kind of endangered national plant medicine in the northern of Xinjiang,China.It mainly contains sesquiterpene coumarins,sulfides,polysaccharides,aromatic compounds and other effective chemical constitutions;Chromatography is used to build the fingerprint and to control the medicine quality in most cases. Both raw plant medicine and specific compounds possess pharmacologic activities such as antibacterial,insecticidal,anti-allergic,and antitumor properties. The present paper summarizes the resource distribution,chemical constituents,fingerprints and pharmacological activities of F. sinkiangensis,to provide reference for its systematic research,effective quality control and efficient development and utilization.
【Key words】 Ferula sinkiangensis K.M.Shen; resource distribution; chemical constituents; fingerprints; pharmacological activities;
- 【文献出处】 国际药学研究杂志 ,Journal of International Pharmaceutical Research , 编辑部邮箱 ,2017年06期
- 【分类号】R284;R285
- 【被引频次】12
- 【下载频次】751