【摘要】 目的探讨亚高原地区人群冠心病相关危险因素及其预防措施。方法统计兰州地区2013年6月—2016年1月经冠状动脉造影及临床症状检查确诊为冠心病的患者共386例,分别对所有患者进行统一问卷调查统计所有患者的性别、年龄、体质量指数(BMI)、病程、文化程度、高血压、高血脂、冠心病家族史、糖尿病史、日常运动情况、吸烟、酗酒、不合理膳食情况等作为影响因素,使用向后迭代法对影响因素进行考察,以患者血管老化作为因变量建立定序逻辑斯特模型,将考察的各因素代入模型中进行权重分析,研究各因素与冠心病发病的相关性,并对其防治措施进行探讨。结果最终筛选年龄、BMI、性别、冠心病家族史、糖尿病史、高血压、高血脂、吸烟、酗酒、不合理膳食情况、日常运动情况对因变量有显著解释能力的因素作为影响因素,其中年龄、BMI、冠心病家族史、糖尿病史、高血压、高血脂、吸烟、酗酒、不合理膳食情况与血管老化情况呈正相关,为发病危险因素;性别、日常运动情况是此类疾病的保护因素。结论控制冠心病患者的体重,调整其不合理膳食状态,改变其吸烟喝酒等不良生活习惯等可降低患者病情发展的速度,减少死亡的可能性。更多还原

【Abstract】 Objective To investigate the risk factor for coronary heart diseases of people living in a subhigh altitude area. Methods Medical records of 386 coronary heart disease patients diagnosed by coronary arteriongraphy and clinical symptoms in June 2013 to Junuary 2016 were reviewed retrospectively. The age,gender,BMI,duration of disease,degree of education,hypertension,hyperlipidemia,family history of coronary heart diseases and diabetes,situation of activity,smoking,alcohol abuse and irrational diet of all patients were investigated by a questionnare. A backward iteration statistical method was used to investigate the influencing factors for coronary heart diseases. By means of the vascular aging of patients as the dependent variable to establish an ordinal logistic model,all factors were substituted into the model to examine the weight of each factor on the relationship with coronary heart diseases and to explore the relevant preventive measures. Results The age,gender,BMI,hypertension,hyperlipidemia,family history of coronary heart disease and diabetes,smoking,alcohol abuse,irrational diet and the activity of these patients were finally selected and had significant explanatory power with the dependent variable. Age,BMI,hypertension,hyperlipidemia,family history of coronary heart disease and diabetes,smoking,alcohol abuse,irrational diet and vascular aging were positively correlated risk factors,but gender and activity were protective factors. Conclus ion Controlling the body weight of coronary heart disease patients,adjusting the irrational dietary condition,changing the smoking and drinking habits can effectively reduce the development of the disease and the possibility of causing death.更多还原