【摘要】 目的探讨老年血管性痴呆患者血压变异性特点及临床意义。方法将我院收治的血管性痴呆老年患者50例作为观察组,同时收集50例健康老年人作为对照组,比较两组患者血压变异性,同时分析血管性痴呆患者血压变异性与简易智能状态量表评分(MMSE)和日常生活能力评定量表评分(ADL)的相关性。结果与对照组比较,观察组患者24h收缩压变异性显著增加(14.58±4.39 vs.10.58±3.71,P=0.000);24h舒张压变异性显著增加(13.58±3.92 vs.9.12±3.15,P=0.000)。Pearson线性相关性分析显示24h收缩压变异性与MMSE和ADL显著负相关(r=-0.258和-0.214,P<0.05)。结论血管性痴呆老年患者24h收缩压变异性增大,且可能与患者神经功能障碍有关。更多还原

【Abstract】 Objective To investigate the characteristics and clinical meaning of blood pressure variability in elderly patients with vascular dementia. Methods A total of 50 patients with vascular dementia admitted to our hospital were enrolled in this study as the observation group,while 50 healthy elderly were collected as the control group. The blood pressure variability of the both groups were compared. Moreover,the association between the blood pressure variability and mini-mental state of examination(MMSE)and activities of daily living(ADL)were studied. ResultsWhen compared with the control group,patients in the observation group got an elevated level of 24 hours systolic blood pressure variability(14.58±4.39 vs.10.58±3.71,P=0.000),and iastolic blood pressure variability(13.58±3.92 vs.9.12±3.15,P=0.000). Pearson linear correlation analysis showed that 24 h systolic pressure variability was significantly negatively correlated with MMSE and ADL(r=-0.258 and-0.214,P<0.05). Conclusion The 24 hours systolic pressure variability in elderly patients with vascular dementia increases,and it maybe be related to the neurological dysfunction.更多还原