【摘要】 高血压是引起心血管疾病死亡的主要危险因素,据统计全国高血压患病人数达2.7亿。目前,已经有15类,69种药物被批准用于治疗高血压,但治疗率和控制率仍然偏低。因此,有效降低顽固性高血压患者血压,减轻合并症患者靶器官损伤,并减少药物不良反应发生的新型抗高血压药物成为研究重点。本文就近些年来已上市或在研的抗高血压药物的研究现状作一综述,以期为抗高血压的研发和应用提供参考。更多还原

【Abstract】 Hypertension is the leading risk factor for death resulted from cardiovascular diseases. According to the statistics,the number of patients with hypertension in China is 270 million. At present,15 classes and 69 drugs have been approved for the treatment of hypertension,however,the treatment rate and the control rate remain low. Therefore,the research focusing on new antihypertensive drugs are how to effectively reduce the blood pressure in patients with refractory hypertension,reduce the target organ damage in patients with complications, and reduce adverse drug reactions. This paper summarized the recent research progress of anti-hypertensive drugs on the market or in development,so as to provide references for development and application of antihypertensive drugs.更多还原