Objective To explore the possibility of inducing the differentiation of human adipose-derived stem cells(hADSCs)into epidermal cells by co-culture with aminionic cells in vitro. Methods HADSCs were isolated and cultured in vitro, the third passage of which were co-cultured with human amniotic cells(HACs) in a medium supplemented with epidermal growth factor(EGF). The morphological change of hADSCs was observed by light microscopy, and the cells were identified by immunofluorescent staining. Results The numb...