【摘要】 目的评价超早期颅骨缺损钛网修补术的安全性及有效性。方法因颅脑外伤或脑血管意外行标准大骨瓣减压手术治疗患者240例,按颅骨缺损修补时机不同分为超早期组(n=150)和对照组(n=90),分别在术后30~60 d、90~180 d进行颅骨缺损钛网修补术。比较两组手术时间、术中出血、术后并发症、Barthel指数。结果超早期组手术时间、术中出血、皮下积液发生率低于对照组(P<0.01或0.05),而去骨瓣减压术后4个月Barthel指数高于对照组(P<0.01)。结论超早期颅骨缺损钛网修补术安全、有效,有助于神经功能康复,提高生活质量。更多还原

【Abstract】 Objective To evaluate the safety and efficacy of ultra-early cranioplasty with titanium mesh for skull defect.Methods A total of 240 patients with large decompressive craniectomy due to craniocerebral trauma or cerebrovascular accident underwent the titanium mesh cranioplasty 30-60 days(ultra-early group,n=150)or 90-180 days(control group,n=90)after decompression.Operation time,intraoperative hemorrhage,postoperative complications and Barthel index were compared between two groups.Results Compared with control group,operation time,intraoperative hemorrhage,and subcutaneous hydrops were decreased(P<0.01 or 0.05),while 4-month Barthel index after craniectomy was increased(P<0.01)in ultra-early group.Conclusion The ultra-early cranioplasty with titanium mesh is safe and effective for skull defect,which is beneficial to neurological rehabilitation and quality of life.更多还原