Objective To investigate the effects of high intensity focused ultrasound(HIFU)combined laparoscopic myomectomy(LM) treating uterine myoma of intramural muscle. Methods Thirty cases of uterine myoma of intramural muscle were administrated to LM(laparoscopic group) and 30 cases of uterine myoma of intramural muscle were treated with LM combined with HIFU(combination group). Operation time, intraoperative bleeding volume, anal exhaust time, decreasing value of hemoglobin, time of off-bed, wound healing time, ...