Objective To establish and validate simultaneous recording of cystometrography( CMG)and external urethral sphincter electromyography( EUS EMG) in mice. Methods Twelve female,agematched C57 BL/6 mice were anesthetized,and the pudendal canal was located bilaterally,followed by implantation of a polyethylene catheter into the bladder for simultaneous recording of CMG,leak point pressure( LPP) and EUS EMG. After bilateral pudendal nerve transection( PNT),the LPP and EUS EMG recording was repeated on the same mi...
【基金】
国家自然科学基金青年科学基金(81500579)~~
【更新日期】
2017-02-03
【分类号】
R69
【正文快照】
bladder pressure and maximum bladder pressure during voiding were also significantly reduced after PNT(16.4±1.2 vs 7.4±0.7 cm H2O,P<0.001;26.7±1.7 vs 15.9±1.1 cm H2O,P<0.001;35.5±2.0 vs22.8±1.1 cm H2O,P<0.001,respectively).Conclusion Simultaneous re
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