【摘要】 目的:探讨脓毒症预后的临床特点及其相关危险因素,为临床改善脓毒症预后提供依据。方法:回顾性收集115例脓毒症患者的临床资料,依据预后情况分为死亡组(n=40)和存活组(n=75),采用病例对照研究的方法,应用单因素和多因素法来分析影响脓毒症预后死亡的相关危险因素。结果:脓毒症预后死亡率为34.8%(40/115);多因素分析结果显示年龄(OR=7.071)、并发急性肾损伤(OR=4.175)、器官衰竭数目(OR=2.440)、尿素氮(OR=3.080)、C反应蛋白(OR=1.859)、APACHEⅡ评分(OR=5.256)等因素均为脓毒症预后的危险因素。结论:脓毒症预后死亡率较高,其高危因素包括高龄、并发急性肾损伤、多器官功能衰竭、尿素氮和C反应蛋白升高、APACHEⅡ评分高等,应针对这些高危因素采取必要的干预措施。更多还原

【Abstract】 Objective:To explore clinical features and correlated risk factors of prognosis of sepsis patients,then provide basis for improving prognosis of sepsis.Methods:Retrospectively collecting 115 cases data of sepsis patients,these cases were divided into death group(n=40) and survival group(n=75) according to the prognosis.With Case-Control study method,the correlated risk factors of prognosis death of sepsis were analyzed by single and multiple factors analysis methods.Results:The death rate of sepsis prognosis was34.8%(40/115).Multiple factors analysis result showed that the factors of age(OR=7.071),complication of acute kidney injury(OR=4.175),the numbers of organ failure(OR=2.440),urea nitrogen(OR=3.080),C reactive protein(OR=1.859) and APACHEⅡscore(OR=5.256) were the risk factors of sepsis prognosis.Conclusion:The death rate of sepsis prognosis lies in a high rate.The high risk factors of sepsis prognosis include high age,complication of acute kidney injury,multiple organ failure,urea nitrogen and C reactive protein increased,high APACHEⅡ score.Intervention measures should be adopted to aim directly at these high risk factors.更多还原