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三种治疗策略用于晚期肺癌患者后AFP、CA19-9、CEA水平变化的临床研究

Clinical Study on the Changes of Three Treatment Strategies for Patients with Advanced Lung Cancer of AFP,CA19-9 and CEA Level

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【作者】 刘长江徐晓荣郑亮陈晨韩蕃颉周玉法

【Author】 Liu Chang-jiang;Xu Xiao-rong;Zheng Liang;Department of Respir Medicine,Laiwu City People’s Hospital,Shandong Province;

【机构】 山东省莱芜市人民医院呼吸内科

【摘要】 目的:分析探讨不同治疗策略用于晚期肺癌患者的临床疗效。方法:在2015年4月~2015年12月选取我院收治的肺癌晚期无手术指征患者及术后复发患者中资料完整者共89例。所有患者随机进行分为三组,包括静脉化疗组、中药治疗+化疗组及对症止痛组。结果:采用静脉化疗,或中药治疗+化疗或对症止痛支持治疗后,血清肿瘤标志物标CEA,CA125,CYFRA21-1及NSE的检测结果显示,治疗前三组患者各指的差异无统计学意义(P>0.05)。结论:综合考虑结果发现,对于晚期无手术指征患者和术后复发的患者,采用中药治疗+化疗的临床疗效最佳,患者的生活质量提高明显,而对症止痛组次之,静脉化疗组患者的生活质量最差。

【Abstract】 Objective:To analyze the clinical efficacy of different treatment strategies for patients with advanced lung cancer.Methods:From Apri 2015 to Dec 2015,89 cases of patients with advanced non surgical indications and postoperative recurrence of lung cancer in the author’s hospital were selected.All patients were randomly divided into three groups,including intravenous chemotherapy group,Chinese medicine treatment + chemotherapy group and symptomatic pain relief group.Results.-Using intravenous chemotherapy,or herbal treatment + chemotherapy or symptomatic pain after treatment,serum tumor markers CEA,CA125,CYFRA21-1 and NSE detection results showed no statistically significant difference between the three groups before treatment each finger(P > 0.05).Conclusion:Considering the results found for late recurrence in patients with surgery and postoperative syndrome patients,treated with traditional chemotherapy + best clinical curative effect,improve the life quality of the patients obviously,and symptomatic pain group,intravenous chemotherapy group were the worst quality of life.

  • 【文献出处】 中国医药导刊 ,Chinese Journal of Medicinal Guide , 编辑部邮箱 ,2017年01期
  • 【分类号】R734.2
  • 【被引频次】3
  • 【下载频次】50
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