【摘要】 目的评价山西省儿童大骨节病病情及防治效果,为实现大骨节病消除目标提供依据。方法 2012—2015年对全省35个大骨节病区县开展2次病情调查,每个县随机抽取5个病区乡(镇,不足5个则全部抽取),每个乡(镇)随机抽取3个病区村(不足3个则全部抽取),所调查病区村的7~12岁儿童全部进行临床及X线检查,并了解调查村防治措施落实情况;按照《重点地方病控制和消除评价办法》,评价大骨节病防治技术和管理指标。结果第一次共调查了318个病区村、10 872名7~12周岁儿童,X线检出5例干骺端阳性、阳性检出率0.046%;第二次共调查了293个病区村、10 510名7~12周岁儿童,X线未检出阳性病例;X线检出率差异无统计学意义(χ2=3.067,P>0.05);所有调查的病区村7~12周岁儿童未检出大骨节病临床病例,以村为单位的X线阳性检出率在3%以下,且绝大多数村为零检出,无手部骨端改变病例;大骨节病防治工作组织管理得分均在85分及以上。结论山西省35个大骨节病病区县均达到消除标准;应继续加强大骨节病病情监测和健康教育工作,持续巩固防治成果。更多还原

【Abstract】 Objective To evaluate the epidemic situation and control effect on Kaschin-Beck disease(KBD) among children in Shanxi province and provide scientific basis for the goal of KBD elimination. Methods Investigations on epidemic situation of KBD were conducted twice in 35 endemic counties within five years. Three endemic villages were selected randomly from each endemic township(if less than 3 villages, selected all); five endemic townships were selected from each county randomly(if less than 5 townships, selected all). The clinic and X-ray examination were carried out in the children aged from 7 to 12 years in the selected endemic villages. Meanwhile, the implementation of prevention and treatment measures were surveyed in the villages. The evaluation on KBD prevention techniques and management were conducted according to the Evaluation Protocol for the Control and Elimination on Key Endemic Diseases. Results In the first investigation, 5 children with positive metaphysis were found by X-ray examination among 10 872 children from 318 KBD endemic villages, with detection rate of 0.046%. No positive metaphysis case was found in the second investigation in 10 510 children from 293 KBD endemic villages. There was no statistical difference in positive X-ray detection rates(χ2=3.067, P>0.05). No clinic case was found among the children in all KBD endemic villages. Every positive X-ray detection rate was lower than3% in all villages. No clinic cases were detected in most villages, and no case with change of distal end of phalanx was found. Indicators of KBD management for prevention and control were scored all more than 85. Conclusions All of 35 KBD endemic counties in Shanxi province achieve the standard of KBD elimination. The surveillance and health education on KBD should be enhanced to keep the effects of prevention and treatment.更多还原