【摘要】 近年来,卟啉-多肽的超分子组装体系的研究受到了国内外学者的广泛关注,已成为超分子化学、生物材料科学研究的前沿领域之一。卟啉-多肽超分子组装体系因具有结构和功能多样化以及良好的生物相容性等优点,在生物传感、药物治疗、分子识别和光电器件等方面展示出巨大的应用潜力。文章综述了卟啉和多肽超分子构筑模块的分子结构设计、组装体的形貌调控、组装体应用3个方面的主要研究进展,介绍了卟啉与多肽分子之间的主要非共价作用方式,包括分子间静电相互作用、氢键、配位键、亲水/疏水性等,分析了该领域当前研究的焦点及亟需解决的问题。更多还原

【Abstract】 The supramolecular assembly systems of porphyrin-peptides have attracted considerable research interest in the field of supramolecular chemistry and biomaterials. Porphyrin-peptides assembly systems exhibit great potential for various applications such as biosensor,biomedicine,molecular recognition and optoelectronic devices due to the structural diversity,facile function and excellent biocompatibility. This paper reviews recent developments in the assembly of porphyrin-peptides from the perspectives of molecular design for the building blocks,assembly morphology control and assembly application. Moreover,it also provides an introduction about the main non-covalent interactions between porphyrin and peptides,including electrostatic interaction,hydrogen bond,coordination bond and hydrophilic/hydrophobic interaction,as well as the key issues and focus in this field for further research.更多还原