【摘要】 目的:研究血清中二十碳五烯酸与花生四烯酸(EPA/AA)的比值同冠状动脉疾病关系。方法:收集2014年6月至2016年6月36名伴有间歇性跛行的动脉硬化闭塞症(arteriosclerosis obliterans,ASO)门诊患者作为观察组,24例高胆固醇血症门诊患者作为对照组,并测量血清EPA/AA值。同时比较两组患者年龄、性别、体质指数、吸烟、饮酒和糖尿病等情况。结果:两组患者年龄、体质指数、糖尿病的发病率等指标比较,差异具有统计学意义(P<0.05);ASO组血清EPA/AA比值较对照组降低(P<0.05)。结论:ASO患者EPA/AA值较高胆固醇血症患者低,推测血清脂肪酸水平与ASO是有关联的。更多还原

【Abstract】 Objective: To examine the relationship between the ratio of serum Eicosapentaenoic acid to Arachidonic acid( EPA/AA) and arteriosclerosis obliterans( ASO). Methods: Serum EPA/AA was calculated between ASO group( n = 36,patients with intermittent claudication) and control group( n = 24,patients with hypercholesterolemia without ASO) from June 2014 to June 2016. At the same time,the age,sex,body mass index,smoking,drinking and diabetes were compared between the two groups. Results: The two groups had statistical differences in age,body mass index,and diabetes incidence( P < 0. 05). The serum EPA/AA in ASO group was lower than that in the control group( P < 0. 05). Conclusion: Patients with ASO were more likely to have a low EPA/AA. Thus,there is a relation between the ratio and ASO.更多还原