【摘要】 目的:总结超声内镜引导下无水乙醇灌洗术(endoscopic ultrasonography ethanol lavage,EUS-EL)治疗胰腺浆液性囊性肿瘤(serous cystic neoplasm of pancreas,SCN)的临床疗效及安全性,为临床治疗提供参考。方法:选择200例胰腺浆液性囊性肿瘤患者,随机分为观察组和对照组两组各100例。观察组患者行EUS-EL治疗,对照组患者行超声内镜引导下囊液抽吸术,对比两组患者的腹痛缓解情况、囊肿平均直径,并发症、复发率。结果:观察组腹痛缓解率优于对照组(P<0.05);治疗后两组患者囊肿平均直径均降低,观察组降低更明显(P<0.05);两组均未出现发热、出血等并发症,对照组复发率高于观察组(P<0.05)。结论:EUS-EL治疗胰腺浆液性囊性肿瘤效果明显,可以改善患者临床症状,降低囊肿复发,具有实用价值。更多还原

【Abstract】 Objective: To summarize the clinical efficacy and safety of endoscopic ultrasonography-guided enthanol lavage( EUS-EL) in the treatment of pancreatic serous cystic neoplasm( SCN),so as to provide reference for clinical treatment. Methods: 200 cases of pancreatic SCN patients were randomly divided into experimental group and control group,100 cases in each group. Patients in experimental group underwent EUS-EL treatment and those in control group underwent endoscopic ultrasonography-guided( EUS) cyst aspiration. The abdominal pain relief condition,average diameter of cyst and rates of complications and recurrence were compared between the two groups. Results: The abdominal pain relief rate in observation group was significantly better than that in control group( P < 0. 05). After treatment,the average diameters of cyst in the two groups decreased,and the drop level in observation group was significantly lower than that in control group( P < 0. 05). There were no complications such as fever and hemorrhage in the two groups,and the recurrence rate in control group was higher than that in observation group( P < 0. 05).Conclusion: EUS-EL in the treatment of pancreatic SCN can improve the patient’s clinical symptoms and reduce cyst recurrence,which is worthy of implementing.更多还原