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石家庄地区用血医院患者输注去白悬浮红细胞储存时长的现状分析

Storage analysisof red blood in leukocyte-depleted medium forclinical transfusion in Shijiazhuang area

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【作者】 赵凤绵刘晓彦王丽莎崔玉兰张燕李文策常缨杨建强李玮卢丽芬

【Author】 ZHAO Fengmian;LIU Xiaoyan;WANG Lisha;CUI Yulan;ZHANG Yan;LI Wence;CHANG Ying;YANG jianqiang;LI Wei;LV Lifen;Hebei Province Blood Center;

【机构】 河北省血液中心

【摘要】 目的对2013-2016年河北省血液中心供血范围内用血医院患者输注红细胞的储存天数和过期报废单位数进行统计分析,以评估中心的供血能力和患者用血的新旧程度,为中心合理调控红细胞库存量,规范血液发放原则提供数据参考和指导性建议。方法统计各年发往不同级别医院去白悬浮红细胞及储存时长等相关数据,计算患者所用红细胞平均储存天数、不同血型储存天数,并进行统计学分析,P<0.05为有统计学差异。结果 4年来,总发血量、送血量和观察数据量(U)逐年增加;市区内医院用血量占总送血量的2/3以上,郊县医院用血量占比不足总送血量的1/3;除AB血型较低外,患者所用其它3个血型红细胞平均储存天数郊县医院均高于市区医院;各血型红细胞平均储存天数呈持续性逐年增加的趋势,患者使用O型红细胞平均储存18 d左右,B型近20 d,A型和AB型在20 d以上;2013-2015年报废血量和千分率呈逐年下降趋势,2016年出现回升。结论本中心在充分满足临床用血需求的同时,整体库存周转量不断加大,红细胞平均储存天数延长,供血辖区内患者输注的血液均超过2周。

【Abstract】 Objective This study aims toanalyzethe current storage status of the leukocyte-depletedtransfusion-readyred blood cells( RBCs) provided by Hebei province blood centreduring 2013-2016 regarding storage time and expired blood volume.This analysisserves to evaluate the deliver capacity of the centreand the current shelf life of the transfusion-ready bloodfor patients,which would help in better managementof RBCs stored and offerperspectives along withreference data for improved bloodallocation.Methods Statistical analysis was performed by collecting and processingbloodallocation dataregarding the target hospital,allocation time and storage length. The average storage length of patient-transfusedblood was calculated. Results Over thelast 4 years,the total volume of the blood allocated,the blood volume delivered and theamount of observation data keptincreasing. The urban hospitalsconsumedmore than 2/3 of the total volume delivered while the suburban hospitalsreceived the rest. The storage length of RBCs in the suburban areas were much higher thanthat of the urbanhospitals except forthe AB typeblood. Overall,the blood storage length maintained a upgoing trend during the investigated period. Type Opresented a storage length around 18 dandtype Breached 20 d.Type A and AB both exceeded 20 d of storage periods. The blood expiration ratecontinued to drop over 2013-2015. However,it bounced back in 2016. Conclusion Hebei Province Blood Center manage to maintain stable blood supply for clinical applications while successfully coped with a increasing volume of blood. The average storage time of RBC stends to prolong and reached over 2 weeks of storage time. We hereby present several suggestions based on our analysis: 1. The blood center shouldrearrange itsRBCinventory,meeting a storage length around10 d. 2.Abetter balance between urban and suburbanblood allocation could be obtained bypartially assigning fresher blood to the suburban regions,which benefits long-blood management by reducing blood expiration risks. 3. Theconcerned hospitalsshould launch training projects toimprove staff performance in blood applications while a refinedevaluation system could be implemented forpatients pre and post operations. These would generate valuable data for enhanced co-operation between hospitals and the centre. 4.As for patients with special conditionsshould be handled under the"in late,out first"principleto ensure effectiveblood transfusion. 5. The center need to reinforce its supervision over the application of TMIS systemto obtain refined,polished data. Meanwhile TMIS system can be utilized by transfusion departments tomonitorthe hospital blood inventory,creatingactive communication and coordination between hospitalsandthus minimizesthe blood expiration rate.

【基金】 河北省2015年医学科学研究重点课题(20150620)
  • 【文献出处】 中国输血杂志 ,Chinese Journal of Blood Transfusion , 编辑部邮箱 ,2017年11期
  • 【分类号】R457.1
  • 【被引频次】6
  • 【下载频次】49
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