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初诊2型糖尿病患者甲状腺结节影响因素分析

Analysis of Thyroid Nodules and Its Influence Factors in the Newly-diagnosed Type 2 Diabetes Mellitus Patients

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【作者】 崔丽梅刘翠平傅汉菁郑晓敏陶静严晔华李彬陈晓燕

【Author】 CUI Li-Mei;LIU Cui-Ping;FU Han-Jing;ZHENG Xiao-Min;TAO Jing;YAN Ye-Hua;LI Bin;CHEN Xiao-Yan;Department of Endocrinology in Beijing Chuiyangliu Hospital;Department of Endocrinology in Beijing TONGREN Hospital Affiliated to Capital Medical University;

【机构】 北京市垂杨柳医院内分泌科首都医科大学附属北京同仁医院内分泌科

【摘要】 目的探讨影响初诊2型糖尿病(T2DM)患者甲状腺结节的危险因素。方法选择北京市垂杨柳医院内分泌科2015年5月至2016年10月的初诊2型糖尿病患者239例。根据甲状腺彩超结果分为有结节组(n=79)和无结节组(n=160),进行初诊2型糖尿病患者甲状腺结节与临床指标、甲状腺功能的相关性分析。结果初诊2型糖尿病患者甲状腺结节的患病率33.1%;女性患病率44.1%,明显高于男性患病率26.0%。两组间的年龄、血清25羟维生素D[25(OH)D]比较差异有统计学意义(P<0.05)。Logistic回归分析结果显示女性、年龄、吸烟、甲状腺球蛋白抗体(TgAb)与甲状腺结节呈独立正相关(P<0.05)。结论女性、年龄、吸烟、TgAb是初诊2型糖尿病患者甲状腺结节的独立危险因素。

【Abstract】 Objective To observe influence factors between Thyroid Nodules(TN) and clinical characteristics in the newly-diagnosed Type 2 Diabetes Mellitus patients.Methods 239 patients with the newly-diagnosed T2 DM were selected in department of Endocrinology,Beijing Chuiyangliu Hospital.According to ultrasound of thyroid,these patients were divided into two groups:the group with TN(n = 79) and the group without TN(n = 160).Clinical characteristics and thyroid function were compared in these groups.Results The overall prevalence of TN was 33.1%in the newly-diagnosed T2 DM patients.The prevalence of TN in females was 44.1%,higher than that in males,which was 26.0%.There were differences in age and serum25(OH) vitamin D in these groups(P <0.05).The Logistic regression analysis showed that female,age,smoke,TgAb were positive correlated with TN(P <0.05).Conclusion Female,age,smoke,TgAb are important risk factors for Thyroid Nodules in the newly-diagnosed T2DM patients.

  • 【文献出处】 标记免疫分析与临床 ,Labeled Immunoassays and Clinical Medicine , 编辑部邮箱 ,2017年05期
  • 【分类号】R581.1;R587.1
  • 【被引频次】9
  • 【下载频次】102
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