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肝内胆管癌术后复发和生存的危险因素研究

Risk factors associated with recurrence and survival after resection of intrahepatic cholangiocarcinoma

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【作者】 崔广飞高凌

【Author】 CUI Guangfei;GAO Ling;Department of Gastroenterology & Hepatology,First People’s Hospital of Shangqiu;

【机构】 商丘市第一人民医院胃肠肝胆外科

【摘要】 目的探究肝内胆管癌(ICC)预后特征及复发、生存相关的危险因素。方法回顾性纳入65例ICC患者,其中复发组42例,无复发组23例,分析术后随访资料,进行生存分析和回归分析,确定与术后复发、生存相关的危险因素。结果平均随访时间33.1个月,肿瘤直径、血管受累、淋巴结受累可影响患者复发情况,而血管受累、淋巴结受累、接受放/化疗可影响患者生存时间。结论淋巴结和血管受累是影响ICC患者术后复发和生存的独立危险因素,对于预测预后具有重要参考意义。

【Abstract】 Objective To investigate the prognostic characters and risk factors associated with recurrence and survival after resection of intrahepatic cholangiocarcinoma(ICC). Method 65 of patients with ICC were enrolled and divided into recurrence group(42 cases) and non-recurrence group(23 cases). The follow-up data after surgery were retrospectively analyzed, and the risk factors associated with recurrence and survival after surgery were characterized by survival analysis and regression analysis. Result The median follow-up time was 33.1 months. Tumor diameter, vascular invasion and lymph node involvement appeared to affect cancer recurrence, and vascular invasion, lymph node involvement and radiotherapy/chemotherapy could have certain effects on survival time. Conclusion Lymph node and vascular involvement is an independent risk factor for recurrence and survival of ICC patients after surgery, and has clinical significance in prognosis prediction.

【关键词】 肝内胆管癌复发生存
【Key words】 intrahepatic cholangiocarcinomarecurrencesurvival
  • 【分类号】R735.8
  • 【被引频次】3
  • 【下载频次】73
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