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壳聚糖及其衍生物在预防术后粘连方面的研究进展
Research Advances on Application of Chitosan and Its Derivatives in Postoperative Anti-Adhesion
【摘要】 术后粘连是外科手术中最常见的并发症之一,同时增加了再手术的难度和其他并发症的发生,因此预防术后粘连是外科领域亟待解决的一个难题。近年来各种抗粘连的药物和材料成为国内外专家研究的热点。壳聚糖具有成本低、方便使用、生物相容性良好、无细胞毒性等特点,其作为医用抗粘连材料有着巨大的潜力。本文从壳聚糖的来源、制备方法及其在抗粘连方面的研究进展做了概括总结。
【Abstract】 The formation of peritoneal adhesions represents one of the most common complications after abdominal surgery,and it increases the difficulty of re-operation. Thus,preventing postoperative adhesions is a major problem in the field of surgical medicine. As a result,the study of anti-adhesion drugs and materials has become a hot topic for experts and scholars in recent years. The chitosan is inexpensive,highly biocompatible,nontoxic and easy to use,which make it a promising anti-adhesion material. Here,we reviewed the sources and preparation of chitosan and the research progress on preventing adhesion.
【Key words】 Chitosan; Carboxymethyl chitosan; Postoperative anti-adhesion;
- 【文献出处】 山东农业科学 ,Shandong Agricultural Sciences , 编辑部邮箱 ,2017年01期
- 【分类号】R318.08
- 【被引频次】5
- 【下载频次】268