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延安地区中老年高血压患者的体质量指数及遗传方式研究

Study on mode of inheritance and relationship between BMI and prevalence rate of hypertension of middle and elderly people in Yanan

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【作者】 慕明涛毕云霍满鹏张静刘俊俊

【Author】 MU Ming-tao;BI Yun;HUO Man-peng;ZHANG Jing;LIU Jun-jun;Department of Medical Genetics and Cell Biology,Collage of Medical Sciences,Yan′an University;Affiliate Hospital,Yan′an University;

【机构】 延安大学医学院医学遗传学与细胞生物学教研室延安大学附属医院心内科

【摘要】 目的探讨中老年人体质量指数与高血压发生的关系及其遗传方式。方法标准法测量并计算456名中老年人的身高、血压、体质量指数,按不同分组,分析高血压患病情况及其遗传方式。结果男性肥胖组(BMI≥25)的高血压患病率(48.21%),明显高于正常组(BMI18.5~24.9,29.32%);女性肥胖组患病率(52.38%)明显高于BMI正常组(29.75%)。遗传方式应为多基因遗传。结论肥胖是影响高血压患病率的重要因素,高血压的发生与遗传和环境都有关系。

【Abstract】 Objective:To study mode of inheritance and the relationship between BMI and the prevalence rate of hypertension. Methods:Mode of inheritance was analysed and the weight,blood pressue and height of 456 people were measured with standardized methods.The investigated people were grouped by age,sex and BMI. Results:For male,the prevalence rate(48.21%)of hypertension for the obesity group(BMI≥25)was obviously higher than the normal group(29.32%),the prevalence rate of hypertension obesity group(52.38%)was obviously higher than that of the normal group(29.75%)for female.Mode of inheritance was polygenic inheritance. Conclusion:Obesity is an important factor resulting in hypertension.There is relationship between hypertension and heredity and environment.

【基金】 陕西省科学技术研究发展计划(2011K13-02-06);延安市科学技术研究发展计划项目(2013-KW31);延安大学自然科学研究计划项目(YDQ2013-04)
  • 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2016年07期
  • 【分类号】R544.1
  • 【被引频次】1
  • 【下载频次】52
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