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用于乳腺癌诊断的超声弹性图像特征选择与分类实验

Experiments on the Feature Selection and Classification of Ultrasound Elastography Images for the Diagnosis of Breast Cancers

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【作者】 张耀楠张永亮肖杨

【Author】 ZHANG Yaonan;ZHANG Yongliang;XIAO Yang;College of Electronics and Information Engineering,Xi’an Siyuan University;Sino-Dutch Biomedical and Information Engineering School,Northeastern University;Institute of Biomedical and Health Engineering,Shenzhen Institutes of Advanced Technology,Chinese Academy of Science;

【机构】 西安思源学院电子信息工程学院东北大学中荷生物医学与信息工程学院中国科学院深圳先进技术研究院生物医学与健康工程研究所

【摘要】 乳腺癌是女性最常见的恶性肿瘤,而怎样利用超声弹性图像定量地诊断乳腺癌还是尚未解决的问题。该文根据乳腺肿块图像弹性信息,提取5个弹性特征来描述肿瘤的弹性属性;提取肿块的4个灰度共生矩阵特征来描述乳腺肿块的纹理特征。为进一步研究应用SVM分类器,对这些特征进行训练而完成分类,并且运用一致性、分类精度、ROC曲线及曲线下面积AUC对分类结果进行评估。利用超声弹性成像设备从实际病人采集数据,共采集了142例患者195个病灶的图像数据。实验结果表明,提取出的弹性特征分类性能良好,而支持向量机比较适合乳腺图像分类,分类精度比较高,有比较好的诊断价值。同时也发现,提取的灰度共生矩阵特征诊断价值比较低,参考意义较少。

【Abstract】 Breast cancers are the most common malignant tumors in women, and how to use ultrasound to diagnose breast cancers quantitatively is still an unsolved problem. This paper extracts five elastic features based on the elastography images of the breast tumors, furthers extract four features related to gray co-occurrence matrix to describe the texture of breast masses. we study the application of SVM classifier to classify these features, and uses the consistency, classification accuracy, ROC curve and AUC(area under the curve) to assess the classification results. we used ultrasound imaging technique to collect data from the actual patients, with the data of 195 lesions in 142 patients. Experimental results show that the classification performance of the elastic features is good, and the support vector machine is suitable for breast image classification, and its classification accuracy is high, which provides a good value for diagnosis. Meanwhile, it is found that the extracted features related to gray level co-occurrence matrix have a low diagnostic value.

【关键词】 超声弹性图像纹理SVM分类器乳腺癌
【Key words】 ultrasoundelastography imagestextureSVM classifierbreast cancer
【基金】 西安思源学院校级重大科研项目(XASY-B1601)
  • 【文献出处】 中国医疗器械杂志 ,Chinese Journal of Medical Instrumentation , 编辑部邮箱 ,2016年06期
  • 【分类号】R445.1;R737.9
  • 【被引频次】3
  • 【下载频次】107
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