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安宫牛黄丸联合经颅低频磁刺激对帕金森病患者运动和情感障碍的改善作用

Angong Niuhuang pills Combined with Transcranial Magnetic Stimulation in Improvement of Dyskinesia and Affective Disorder of Patients with Parkinson’s Disease

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【作者】 姜海波高忠明王小川叶小军卢晓东尹厚民冯蔚

【Author】 JIANG Haibo;GAO Zhongming;WANG Xiaochuan;YE Xiaojun;LU Xiaodong;YIN Houmin;FENG Wei;Medical Neurology,The Affiliated Hospital of Hangzhou Normal University;Medical Neurology,The Second Affiliated Hospital,Zhejiang University School of Medicine Hangzhou;

【机构】 杭州师范大学附属医院神经内科浙江大学医学院附属第二医院神经内科

【摘要】 目的:研究安宫牛黄丸联合经颅低频磁刺激对帕金森病(PD)患者运动和情感障碍的改善作用。方法:选取2010年4月—2015年3月期间医院收治的100例PD患者作为研究对象,将患者随进分为两组:观察组50例,接受安宫牛黄丸联合经颅低频磁刺激治疗(TMS);对照组50例,接受经颅低频磁刺激治疗。比较两组患者的临床疗效、治疗前后的UPDRS评分、HAMD和HAMA评分。结果:观察组患者的有效率为92.00%,对照组为78.00%,差异具有统计学意义(P<0.05)。两组患者治疗后的UPDRS总分,UPDRS I、UPDRSII和UPDRSIII评分,HAMD和HAM评分的差异具有统计学意义(P<0.05)。结论:安宫牛黄丸联合经颅低频磁刺激可以明显改善帕金森患者的运动和情感障碍。

【Abstract】 Objective: To study the effect of Angong Niuhuang Pills combined with transcranial magnetic stimulation in improvement of dyskinesia and affective disorder of patients with parkinson’s disease. Methods: From April 2010 to March 2015,a total of 100 patients were chosen as study objects: 50 in study group who were treated with Angong Niuhuang Pills combined with transcranial magnetic stimulation and 50 in control group who were treated with transcranial magnetic stimulation. Results: The effect rate of study group was 92. 00% and that of control group was 78. 00%. The difference had statistical significance( P < 0. 05). After treatment,the difference between two groups’ UPDRS,UPDRS I,UPDRS II,UPDRS III,HAMD and HAMA had statistical significance( P < 0. 05). Conclusion: Angong Niuhuang Pills combined with transcranial magnetic stimulation can significantly improve the dyskinesia and affective disorder of patients with Parkinson’s disease.

【基金】 杭州市科技发展计划项目(20130633B14)
  • 【文献出处】 中华中医药学刊 ,Chinese Archives of Traditional Chinese Medicine , 编辑部邮箱 ,2016年06期
  • 【分类号】R742.5
  • 【被引频次】9
  • 【下载频次】242
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